The prognostic value of the prognostic nutritional index and inflammation-based markers in obstructive colorectal cancer
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ORIGINAL ARTICLE
The prognostic value of the prognostic nutritional index and inflammation‑based markers in obstructive colorectal cancer Ryuichiro Sato1 · Masaya Oikawa1 · Tetsuya Kakita1 · Takaho Okada1 · Tomoya Abe1 · Takashi Yazawa1 · Haruyuki Tsuchiya1 · Naoya Akazawa1 · Masaki Sato1 · Tetsuya Ohira2 · Yoshihiro Harada2 · Haruka Okano2 · Kei Ito2 · Takashi Tsuchiya1 Received: 10 February 2020 / Accepted: 3 April 2020 © Springer Nature Singapore Pte Ltd. 2020
Abstract Purpose Inflammation-based markers predict long-term outcomes of various malignancies. We investigated the relationship between these markers and the long-term survival in obstructive colorectal cancer (OCRC) patients with self-expandable metallic colonic stents (SEMSs) who subsequently received curative surgery. Methods We retrospectively analyzed 72 consecutive pathological stage II and III OCRC patients between 2013 and 2019. The prognostic significance of the prognostic nutritional index (PNI), neutrophil–lymphocyte ratio (NLR), lymphocyte– monocyte ratio (LMR), and platelet–lymphocyte ratio (PLR) was evaluated. Results The overall survival (OS), cancer-specific survival, and disease-free survival (DFS) were significantly shorter in the PNI
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