RNAi and Small Regulatory RNAs in Stem Cells Methods and Protocols
This detailed collection provides an accessible compendium of up-to-date methods focused on the study of RNAi and small regulatory miRNAs in stem cells. Beginning with a brief introductory section, the volume continues by exploring methods and protocols f
- PDF / 6,979,755 Bytes
- 306 Pages / 504.63 x 737.01 pts Page_size
- 17 Downloads / 175 Views
Baohong Zhang Editor
RNAi and Small Regulatory RNAs in Stem Cells Methods and Protocols
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
RNAi and Small Regulatory RNAs in Stem Cells Methods and Protocols
Edited by
Baohong Zhang Department of Biology, East Carolina University, Greenville, NC, USA
Editor Baohong Zhang Department of Biology East Carolina University Greenville, NC, USA
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7106-0 ISBN 978-1-4939-7108-4 (eBook) DOI 10.1007/978-1-4939-7108-4 Library of Congress Control Number: 2017944281 © Springer Science+Business Media LLC 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface At present, research in the areas of stem cell biology, RNA interference (RNAi), and small regulatory RNAs are the source of immense scientific and medical interest. Despite their apparent differences, stem cell biology, RNAi, and small regulatory RNAs, including microRNAs (miRNAs), are increasingly being shown to have a great deal in common. Small RNAs, particularly those represented by miRNAs and RNAi, play a central role in the regulation of embryonic and adult stem cell development. Recent research has revealed that in stem cells, small regulatory RNAs, including miRNA and siRNAs, are one of the determinates controlling the state of cell differentiation, with the small RNAs serving as key elements involved in regulatory network control of pluripotent cell fate determination. From a te
Data Loading...
