Synergistic effect of carbon nanotubes, copper and silver nanoparticles as an efficient electrochemical sensor for the t
- PDF / 1,973,256 Bytes
- 12 Pages / 595.276 x 790.866 pts Page_size
- 8 Downloads / 201 Views
Synergistic effect of carbon nanotubes, copper and silver nanoparticles as an efficient electrochemical sensor for the trace recognition of amlodipine besylate drug Gowhar A. Naikoo1 · Umar J. Pandit2 · Mehraj U. D. Sheikh2 · Israr Ul Hassan3 · Gulzar A. Khan2 · Ajmal R. Bhat4 · Ratnesh Das2 · Ridha Horchani5 Received: 6 March 2020 / Accepted: 22 April 2020 / Published online: 28 April 2020 © Springer Nature Switzerland AG 2020
Abstract The electrochemically functionalized multiwalled carbon nanotubes/copper nanoparticles (fMWCNT/CuNPs) carbon paste electrode (fMWCNT/CuNPs-CPE) was successfully modified by silver nanoparticles (AgNPs) via electrocatalytic process. The formation of modified electrode (AgNPs/fMWCNT/Cu NP-CPE) was observed by Field Emission Scanning Electron Microscopy and X-ray diffraction techniques. The as-prepared electrodes were explored for the trace recognition of calcium channel blocker drug amlodipine besylate (ADB) using cyclic voltammetry and electrochemical impedance spectroscopy measurements. Kinetic parameters like electron transfer coefficient (α), charge due to adsorption (Qads), surface coverage (Γ), charge transfer coefficient ( Rct), and apparent electron-transfer rate constant ( kapp) for the designed electrodes were evaluated. The nanoparticles based electrochemical sensor displayed high sensitivity, good selectivity and favorable catalytic ability for the oxidation of amlodipine besylate. The fabricated electrodes showed good reproducibility and stability towards the determination of anti-hypertensive drug ADB. Keywords Electrochemical sensor · Functionalized carbon nanotubes · Amlodipine besylate Abbreviations Ag NPs Silver nanoparticles fMWCNT/Cu NPs Functionalized multiwalled carbon nanotubes/copper nanoparticles CPE Carbon paste electrode CV Cyclic voltammetry MWCNTs Multiwalled carbon nanotubes ADB Amlodipine besylate BR Britton-Robinson FESEM Field Emission Scanning Electron Microscope SWAdV Square wave adsorptive stripping voltammetry
EIS Electrochemical impedance spectroscopy AdSWV Adsorptive square wave voltammetry LOD Limit of detection LOQ Limit of quantification
1 Introduction The development of highly efficient electrochemical sensors using nanostructures of metal and metal oxides has attracted the researchers for the qualitative and quantitative analysis of organic molecules including pharmaceutical drugs and related molecules in biological and
* Gowhar A. Naikoo, [email protected]; [email protected]; Umar J. Pandit, [email protected] | 1Department of Mathematics and Sciences, College of Arts and Applied Sciences, Dhofar University, Salalah, Sultanate of Oman. 2Department of Chemistry, Dr. Harisingh Gour University, Sagar, M.P., India. 3College of Engineering, Dhofar University, Salalah, Sultanate of Oman. 4Department of Chemistry, Govt; Degree College, Bijbehara, Jammu and Kashmir, India. 5College of Science, Sultan Qaboos University, Muscat, Sultanate of Oman. SN Applied Sciences (2020) 2:983 | https://doi.org/10.1007/s42452-020-2807-z
Vol
Data Loading...
