Tissue Engineering From Lab to Clinic
Tissue engineering is a multidisciplinary field incorporating the principles of biology, chemistry, engineering, and medicine to create biological substitutes of native tissues for scientific research or clinical use. Applications of this technology inclu
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Norbert Pallua • Christoph V. Suschek Editors
Tissue Engineering From Lab to Clinic
Editors Univ.-Prof. Dr. med. Norbert Pallua Universitätsklinikum, der RWTH Aachen Klinik für Plastische Chirurgie, Handund Verbrennungschirurgie Pauwelsstr. 30 52074 Aachen Germany [email protected]
Prof. Dr. Christoph V. Suschek Universitätsklinikum, der RWTH Aachen Klinik für Plastische Chirurgie, Handund Verbrennungschirurgie Pauwelsstr. 30 52074 Aachen Germany [email protected]
Illustrator Piotr Gusta 6. Rue du Chemin Vert 94500 Champigny sur Marne, France
ISBN 978-3-642-02823-6 e-ISBN 978-3-642-02824-3 DOI 10.1007/978-3-642-02824-3 Springer Heidelberg Dordrecht London New York © Springer-Verlag Berlin Heidelberg 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: eStudioCalamar, Figueres/Berlin Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
Although efforts to generate bioartificial tissues and organs for human therapies date back to the 80s, these efforts have only come closer to reality in the past 10 years. The possibility of such bioartifical tissues has been fueled by major advances in cell and molecular biology and the development of more sophisticated cell-culture technologies. The term Tissue Engineering has come to a broader application in the last five years and now encompasses the many interdisciplinary fields of knowledge that are crucial to generate or regenerate tissues or even whole organs. Tissue engineering has the potential to revolutionize health care, improving the treatment options and quality of life for millions of people worldwide, yet, saving enormous financial resources in terms of health care costs. One of its defining characteristics is that it draws upon and requires close collaboration among scientists in many diverse specialties. Cell and molecular biologists, biomaterials engineers, advanced imaging specialists, robotics engineers, and developers of equipment such as bioreactors, w
