Cisplatin
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Treatment failure: case report In a retrospective study of 260 patients treated between 2000 to 2015 in USA, one patient [age and sex not stated] was described, who exhibited treatment failure during treatment with cisplatin for metastatic head and neck squamous cell carcinoma to cervical lymph nodes of unknown primary (HN-SCCUP). The patient, who was diagnosed with HN-SCCUP, started receiving radiotherapy administered to adjacent lymph node groups in the unilateral necks. Additionally, the patient received cisplatin [route and dosage not stated]. The patient had undergone a neck dissection (ND) prior to radiation therapy. During follow-up, the diagnostic CT scan revealed recurrence of the disease (treatment failure). Subsequent histopathology examination confirmed both mucosal and nodel relapse outside the radiotherapy field. Kamal M, et al. Patterns of Failure After Intensity Modulated Radiation Therapy in Head and Neck Squamous Cell Carcinoma of Unknown Primary: Implication of Elective Nodal and Mucosal Dose Coverage. Advances in Radiation Oncology 5: 929-935, No. 5, Sep 2020. Available from: URL: http://doi.org/10.1016/ 803519443 j.adro.2020.04.025
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Reactions 5 Dec 2020 No. 1833
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