Maternal predictors and quality of umbilical cord blood units
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Maternal predictors and quality of umbilical cord blood units _ Jastrze˛bska-Stojko . Agnieszka Drosdzol-Cop . Beata Bielec-Berek . Zaneta . Cecylia Jendyk Dariusz Boruczkowski . Tomasz Ołdak . Agnieszka Nowak-Brzezin´ska . Rafał Stojko
Received: 11 July 2017 / Accepted: 14 August 2017 Ó The Author(s) 2017. This article is an open access publication
Abstract The aim of the study was to determine the relationship between the maternal age at delivery and selected properties of the cord blood stem cells. The study included 50 pregnant women aged between 18 and 38 years in which spontaneous labors or elective cesarean sections were performed. Umbilical cord blood was collected immediately after the women were delivered of newborns. The samples were analyzed in the Polish Stem Cells Bank in Warsaw. The highest mean WBC level (p \ 0.05) was observed in the umbilical blood collected from patients aged
35 years and more. Similarly, the highest mean cell viability was observed in the umbilical cord blood collected from patients aged 35 and more. There were no statistically significant correlations between the CD34? cells count and mean cell viability in the umbilical cord blood and the maternal age. With the significance level at p \ 0.001, the females after spontaneous labor revealed a visibly higher WBC level than patients after a cesarean section. The higher mean WBC concentration (24.95 thousand/ll) was observed in the umbilical cord blood of patients aged
B. Bielec-Berek A. Drosdzol-Cop (&) R. Stojko School of Health Sciences in Katowice, Medical University of Silesia Katowice, ul. Medyko´w 12, 40-752 Katowice, Poland e-mail: [email protected]
D. Boruczkowski T. Ołdak Polish Stem Cells Bank, Warsaw, Poland e-mail: [email protected]
B. Bielec-Berek e-mail: [email protected] R. Stojko e-mail: [email protected] _ Jastrze˛bska-Stojko Z. Department of Anaesthesiology and Intensive Therapy, UCK prof. K. Gibin´skiego, Medical University of Silesia, Katowice, ul. Ceglana 35, 40-514 Katowice, Poland e-mail: [email protected]
T. Ołdak e-mail: [email protected] A. Nowak-Brzezin´ska Institute of Computer Science, Faculty of Computer Science and Material Science, Silesian University, ul. Bedzinska 39, 41-200 Sosnowiec, Poland e-mail: [email protected]
A. Drosdzol-Cop C. Jendyk R. Stojko Department of Obstetrics and Gynecology, The Boni Fratres Catoviensis Hospital, ul. Ks. Leopolda Markiefki 87, 40-211 Katowice, Poland e-mail: [email protected]
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Cell Tissue Bank
35 and more after spontaneous labors. In the same group, the umbilical cord blood was also characterized by the highest mean cell viability (98.72%). The number of nucleated cells in the umbilical cord blood collected in the perinatal period increases together with the maternal age. In the course of physiological spontaneous labors, the collected umbilical cord blood has more nucleated cells as compared with elective caesarian sections. Keywords Steam cell Umbilical cord blood Maternal age Cord blood banking Vaginal birth Caesare
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