Metagenomic Systems Biology Integrative Analysis of the Microbio
The book serves as an amalgamation of knowledge and principles used in the area of systems and synthetic biology, and targets inter-disciplinary research groups. The readers from diversified areas would be benefited by the valuable resources and
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Metagenomic Systems Biology Integrative Analysis of the Microbiome
Metagenomic Systems Biology
Shailza Singh Editor
Metagenomic Systems Biology Integrative Analysis of the Microbiome
Editor Shailza Singh Computational and Systems Biology Lab National Centre for Cell Science Pune, Maharashtra, India
ISBN 978-981-15-8561-6 ISBN 978-981-15-8562-3 https://doi.org/10.1007/978-981-15-8562-3
(eBook)
# Springer Nature Singapore Pte Ltd. 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Contents
1
Gut Microbiome in Microbial Pathogenicity . . . . . . . . . . . . . . . . . . . Pragya Misra and Shailza Singh
2
Role of Genome-Wide Association Studies in Host Genetics: Toward Understanding of Microbiome Association . . . . . . . . . . . . . . Rashmi Dahiya, Taj Mohammad, and Md. Imtaiyaz Hassan
1
37
3
Understanding Microbiome Science Through Big Data Analysis . . . . Aditya Narayan, Ajeet Singh, and Shailesh Kumar
4
Comparative Genomics Facilitates Drug Target Selection and Develops Intervention Strategies Against Leishmania Infections . . . . Anindita Paul and Sushma Singh
75
Culture-Independent Omics-Techniques for Microbiome-Based Molecular Therapeutics Against Infectious Diseases . . . . . . . . . . . . . Santanu Sasidharan, K. Divakar, and Prakash Saudagar
95
5
55
6
The Earth’s Microbiome: Significance in Sustainable Development and Impact of Climate Changes . . . . . . . . . . . . . . . . . . 115 Deepika Goyal, Manali Vaijanapurkar, Eden Jacques, Janmejay Pandey, and Om Prakash
7
Microbiome for Personalized Medicine . . . . . . . . . . . . . . . . . . . . . . . 141 Preeti Rathi, Deepanshu Verma, Ashutosh Singh, and Neha Garg
8
Metagenomic I
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