miRNA Biogenesis Methods and Protocols
This detailed volume collects chapters that seek to expand our knowledge of molecular events and extended molecular networks in gene regulation. The contents explore numerous aspects of miRNA biogenesis, a sophisticated series of events that assure a fine
- PDF / 9,302,657 Bytes
- 238 Pages / 504.63 x 737.01 pts Page_size
- 77 Downloads / 174 Views
Ulf Andersson Vang Ørom Editor
miRNA Biogenesis Methods and Protocols
Methods
in
M o l e c u l a r B i o lo g y
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
miRNA Biogenesis Methods and Protocols
Edited by
Ulf Andersson Vang Ørom Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark
Editor Ulf Andersson Vang Ørom Department of Molecular Biology and Genetics Aarhus University Aarhus, Denmark
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-8623-1 ISBN 978-1-4939-8624-8 (eBook) https://doi.org/10.1007/978-1-4939-8624-8 Library of Congress Control Number: 2018947780 © Springer Science+Business Media, LLC, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer Science+Business Media, LLC part of Springer Nature. The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface miRNAs are well-studied regulatory small RNAs affecting the translation and stability of numerous mRNAs. miRNAs are emerging through a complex biogenesis pathway going from primary transcripts that can be as long as 30 kb to mature miRNA of approximately 21 nts. miRNA biogenesis is a sophisticated series of events assuring a finely tuned regulation of miRNA expression and activity. Understanding miRNA biogenesis better could expand our knowledge of molecular events, contribute to extended molecular networks in gene regulation, and lead to development of new therapeutic interventions. It is my hope that this protocol series will contribute to the further development of knowledge and application of miRNA biogenesis, both in th
Data Loading...
