Planarian Regeneration Methods and Protocols

This volume explores the various facets of planaria as a biomedical model system and discusses techniques used to study the fascinating biology of these animals. The chapters in this book are divided into two parts: Part One looks at the biodiversity of p

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Jochen C. Rink Editor

Planarian Regeneration Methods and Protocols

Methods

in

M o l e c u l a r B i o lo g y

Series editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK

For further volumes: http://www.springer.com/series/7651

Planarian Regeneration Methods and Protocols

Edited by

Jochen C. Rink Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

Editor Jochen C. Rink Max Planck Institute of Molecular Cell Biology and Genetics Dresden, Germany

ISSN 1064-3745     ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7800-7    ISBN 978-1-4939-7802-1 (eBook) https://doi.org/10.1007/978-1-4939-7802-1 Library of Congress Control Number: 2018940265 © Springer Science+Business Media, LLC, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by the registered company Springer Science+Business Media, LLC part of Springer Nature. The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.

Preface Planarian flatworms are remarkable animals. Powered by an abundance of pluripotent adult stem cells, they can regenerate their entire being from minute tissue fragments, scale their body size depending on food availability, and, in some cases, even escape the plight of physiological aging. This fascinating biology has driven the recent re-emergence of planaria as biomedical model system and continues to fuel the rapid expansion of the planarian research community. This book aims to catalyze the latter by providing both a resource for newcomers to the field and a repository of expert information for established planarian labs. Accordingly, the first four chapters provide in-depth coverage of the biodiversity of planarian species, the current