Antimicrobial Peptides and Innate Immunity

Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. This book provides an update on these effector molecules of th

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Pieter S. Hiemstra • Sebastian A. J. Zaat Editors

Antimicrobial Peptides and Innate Immunity

Editors Pieter S. Hiemstra Department of Pulmonology Leiden University Medical Center Leiden Netherlands

Series Editors Prof. Michael J. Parnham, Ph.D. Visiting Scientist Research & Clinical Immunology Unit University Hospital for Infectious Diseases “Dr. Fran Mihaljevic´” Mirogojska 8 HR-10000 Zagreb, Croatia

Sebastian A. J. Zaat Dept. Medical Microbiology Ctr for Infection & Immun. Amsterdam (CINIMA) Academic Medical Center University of Amsterdam Amsterdam Netherlands

Prof. Eugen Faist, MD, FACS Ludwig-Maximilians-University Munich Klinikum Grosshadern Department of Surgery Marchioninistr. 15 81377 Munich Germany

ISBN 978-3-0348-0540-7 ISBN 978-3-0348-0541-4 (eBook) DOI 10.1007/978-3-0348-0541-4 Springer Basel Heidelberg New York Dordrecht London Library of Congress Control Number: 2012956531 # Springer Basel 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

Antimicrobial peptides have been the subject of intense research in the past decades and are now considered as an essential part of the defense system in bacteria, plants, animals, and humans. Whereas lysozyme was identified in the 192