Cardiac magnetic resonance myocardial feature tracking detects quantitative wall motion during dobutamine stress
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POSTER PRESENTATION
Open Access
Cardiac magnetic resonance myocardial feature tracking detects quantitative wall motion during dobutamine stress Andreas Schuster1*, Shelby Kutty2, Asif Padiyath2, Victoria Parish1,3, Paul Gribben2, David A Danford2, Marcus R Makowski4, Boris Bigalke1, Philipp B Beerbaum1,3, Eike Nagel1 From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Summary We sought to determine the feasibility and reproducibility of cardiac magnetic resonance (CMR) myocardial feature tracking (FT) for quantitative wall motion assessment during intermediate dose dobutamine stress magnetic resonance (DSMR) imaging. Background DSMR imaging is an established tool to assess hibernating myocardium and ischemia. Analysis is typically based on visual assessment with considerable operator dependency. CMR-FT is a recently introduced technique for tissue voxel motion tracking on standard steady-state free precession (SSFP) images to derive circumferential and radial myocardial mechanics. Methods 10 healthy subjects were studied at 1.5 Tesla. Myocardial strain parameters were derived from SSFP cine images using dedicated CMR-FT software (Diogenes MRI prototype, Tomtec, Germany). Right ventricular (RV) and left ventricular (LV) longitudinal strain (EllRV and EllLV) and LV long-axis radial strain (ErrLAX) were derived from a 4-chamber view at rest. LV short-axis circumferential strain (EccSAX) and ErrSAX, LV ejection fraction (EF) and volumes were analyzed at rest and during dobutamine stress (10 and 20 μg * kg-1* min-1).
Results In all volunteers strain parameters could be derived from the SSFP images at rest and stress. EccSAX values showed significantly increased contraction with DSMR (rest: -24.1±6.7; 10 μg: -32.7±11.4; 20 μg: -39.2±15.2, p
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