Evaluations of biosynthesized Ag nanoparticles via Allium Sativum flower extract in biological applications
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ORIGINAL ARTICLE
Evaluations of biosynthesized Ag nanoparticles via Allium Sativum flower extract in biological applications K. Velsankar1 · R. Preethi1 · P.S. Jeevan Ram2 · M. Ramesh2 · S. Sudhahar1 Received: 10 April 2020 / Accepted: 23 May 2020 © King Abdulaziz City for Science and Technology 2020
Abstract The eco-friendly phytomediated synthesis of Ag nanoparticles provides better efficient applications than synthetic methods. Ag nanoparticles are considered by researchers due to its specific properties. The phytochemical analysis of Allium Sativum flower extract provides the phytochemicals exist in it. Due to this, the efficient eco-friendly synthesis of Ag nanoparticles via Allium Sativum flower extract has performed. The X-ray diffraction pattern exposes the crystalline nature with the mean crystallite size at 25 nm. The Fourier Transform Infra-Red spectrum displays the phytochemicals involved in the synthesis. The UV–Visible spectrum illustrates the formation of Ag nanoparticles with SPR band at 436 nm. The particle size analyzer demonstrates the size of formed Ag particles in 20–35 nm. The morphological, elemental and structural analyzes demonstrate the formation of spherical shaped Ag nanoparticles. The formation of Ag nanoparticles was confirmed by the appearance of Ag peak in Energy Dispersive X-ray Diffraction spectrum and mapping study. The antimicrobial activity explains the effective antimicrobial effect on human pathogens. The antioxidant activity reports the efficient scavenging property of synthesized Ag nanoparticles. The anti-inflammatory activity reveals the potential ability of protein denaturation on bovine serum albumin. The anti-diabetic activity exhibits much inhibition on α-Amylase. The anticancer activity reports the effective inhibition of synthesized Ag nanoparticles on human MCF-7 breast cancer cells. Keywords Ag nanoparticles · Green synthesis · Phytochemical analysis · Antioxidant activity · Anti-diabetic activity · Anticancer activity
Introduction Nanoscience and nanotechnology provide enormous contributions to the world. It extended its involvement in physics, chemistry, biology, medicine and engineering fields. Novel metal nanoparticles are widely studied due to their specific properties. Many researchers concentrated on optimizing the metal nanoparticles for effective applications (Bar et al. 2009; Kumar et al. 2014a, b; Khalil et al. 2014; Kajani et al. 2014). In this, silver nanoparticles attained more recognition for their specific characteristics namely, high chemical * S. Sudhahar [email protected]; [email protected] 1
Department of Physics, Alagappa University, Karaikudi 630003, India
Department of Biotechnology, Alagappa University, Karaikudi 630003, India
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stability, electrical conductivity, and good antimicrobial activity (Sharma et al. 2009; Ahmed et al. 2016; Li et al. 2007). More than antimicrobial effects, silver nanoparticles are opting for sensing and imaging applications in biological compounds. With the high electrical conduc
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