Molecular Pathogenesis and Signal Transduction by Helicobacter pylori

This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings

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Nicole Tegtmeyer Steffen Backert Editors

Molecular Pathogenesis and Signal Transduction by Helicobacter pylori

Current Topics in Microbiology and Immunology Volume 400

Series editors Rafi Ahmed School of Medicine, Rollins Research Center, Emory University, Room G211, 1510 Clifton Road, Atlanta, GA 30322, USA Klaus Aktories Medizinische Fakultät, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Abt. I, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104 Freiburg, Germany Arturo Casadevall W. Harry Feinstone Department of Molecular Microbiology & Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Room E5132, Baltimore, MD 21205 USA Richard W. Compans Department of Microbiology and Immunology, Emory University, 1518 Clifton Road, CNR 5005, Atlanta, GA 30322, USA Jorge E. Galan Boyer Ctr. for Molecular Medicine, School of Medicine, Yale University, 295 Congress Avenue, room 343, New Haven, CT 06536-0812, USA Tasuku Honjo Faculty of Medicine, Department of Medical Chemistry, Kyoto University, Sakyo-ku, Yoshida, Kyoto 606-8501, Japan Yoshihiro Kawaoka Influenza Research Institute, University of Wisconsin-Madison, 575 Science Drive, Madison, WI 53711, USA Bernard Malissen Centre d’Immunologie de Marseille-Luminy, Parc Scientifique de Luminy, Case 906, 13288, Marseille Cedex 9, France Michael B.A. Oldstone Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA Klaus Palme Institute of Biology II/Molecular Plant Physiology, Albert-Ludwigs-Universität Freiburg, 79104 Freiburg, Germany Rino Rappuoli GSK Vaccines, Via Fiorentina 1, Siena, 53100, Italy Peter K. Vogt Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC-239, La Jolla, CA 92037, USA Honorary Editor: Hilary Koprowski (deceased) Formerly at Biotechnology Foundation, Inc., Ardmore, PA, USA

More information about this series at http://www.springer.com/series/82

Nicole Tegtmeyer Steffen Backert •

Editors

Molecular Pathogenesis and Signal Transduction by Helicobacter pylori Responsible Series Editor: Klaus Aktories

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Editors Nicole Tegtmeyer Division of Microbiology, Department of Biology Friedrich-Alexander University Erlangen-Nuremberg Erlangen Germany

Steffen Backert Division of Microbiology, Department of Biology Friedrich-Alexander University Erlangen-Nuremberg Erlangen Germany

ISSN 0070-217X ISSN 2196-9965 (electronic) Current Topics in Microbiology and Immunology ISBN 978-3-319-50519-0 ISBN 978-3-319-50520-6 (eBook) DOI 10.1007/978-3-319-50520-6 Library of Congress Control Number: 2016959521 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or informa