Proteases in Physiology and Pathology
Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with dysregulation of proteases and the resulting pathophysiological consequences. It highlights the role and regulation of different types of proteases as well
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teases in Physiology and Pathology
Proteases in Physiology and Pathology
Sajal Chakraborti • Naranjan S. Dhalla Editors
Proteases in Physiology and Pathology
Editors Sajal Chakraborti Department of Biochemistry and Biophysics University of Kalyani Kalyani, West Bengal, India
Naranjan S. Dhalla St. Boniface Hospital Research Centre, University of Manitoba, Faculty of Health Sciences, College of Medicine Institute of Cardiovascular Sciences Manitoba, Winnipeg, Canada
ISBN 978-981-10-2512-9 ISBN 978-981-10-2513-6 (eBook) DOI 10.1007/978-981-10-2513-6 Library of Congress Control Number: 2017951624 © Springer Nature Singapore Pte Ltd. 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
This book on Proteases in Physiology and Pathology is dedicated to Professor Kambadur Muralidhar, a distinguished biologist and an outstanding teacher/ educationist of our country. Professor Muralidhar was born in 1948 at Coimbatore, Tamil Nadu, India. He received his PhD from the Indian Institute of Science, Bangalore, in 1976. In the PhD work under Prof. N.R. Moudgal, he demonstrated that the beta subunit of luteinizing hormone can bind to ovarian receptors, which fetched him the Prof KV Giri Memorial Gold medal for the best PhD thesis of the year. He was selected for the first Lectureship in the School of Life
Sciences at the newly founded Central University of Hyderabad in August 1976. During 1979–1981, he has been a Research Associate in the Department of Cell and Molecular Biology at SUNY-Buffalo, New York, USA, and worked with Prof. O.P. Bahl. His work led to the development of the most sensitive RIA for HCG, a pregnanc
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