Mitophagy Methods and Protocols
This volume focuses on mitophagy providing methods and protocols on the methodologies and the background information on monitoring mitophagy. Chapters detail the analysis of mitophagy in connection with Parkinson’s disease, especially young onset Parkinso
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Nobutaka Hattori Shinji Saiki Editors
Mitophagy Methods and Protocols
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Mitophagy Methods and Protocols
Edited by
Nobutaka Hattori and Shinji Saiki Department of Neurology, Juntendo University School of Medicine, Hongo, Bunkyo, Tokyo, Japan
Editors Nobutaka Hattori Department of Neurology Juntendo University School of Medicine Hongo, Bunkyo, Tokyo, Japan
Shinji Saiki Department of Neurology Juntendo University School of Medicine Hongo, Bunkyo, Tokyo, Japan
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7749-9 ISBN 978-1-4939-7750-5 (eBook) https://doi.org/10.1007/978-1-4939-7750-5 Library of Congress Control Number: 2018947388 © Springer Science+Business Media, LLC, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by the registered company Springer Science+Business Media, LLC part of Springer Nature. The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface In 1955, Christian de Duve discovered previously unknown organelles: lysosomes. The discovery significantly contributed to him being awarded a share of the 1974 Nobel Prize in Physiology or Medicine for elucidating “the structural and functional organization of the cell.” More recently, Yoshinori Ohsumi has won the 2016 Nobel Prize in Physiology or Medicine for discovering and elucidating mechanisms underlying autophagy, a fundamental process for degrading and recycling cellular components. Thus, this volume for the methods in molecular biology which focuses on mitophagy, a form of autophagy, is timely and deeply mea
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