Preclinical MRI Methods and Protocols
This volume discusses a variety of preclinical MRI methods and protocols to help technicians and researchers conduct studies in their respective fields. This book is organized into 7 parts: Part 1 covers the basics of MRI physics, relaxation, image contra
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María Luisa García-Martín Pilar López-Larrubia Editors
Preclinical MRI Methods and Protocols
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Preclinical MRI Methods and Protocols
Edited by
María Luisa García-Martín BIONAND, Andalusian Centre for Nanomedicine and Biotechnology, Junta de Andalucía, Universidad de Málaga, Málaga, Spain; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, Málaga, Spain
Pilar López-Larrubia Instituto de Investigaciones Biomédicas “Alberto Sols”, CSIC/UAM, Madrid, Spain
Editors Marı´a Luisa Garcı´a-Martı´n BIONAND, Andalusian Centre for Nanomedicine and Biotechnology Junta de Andalucı´a Universidad de Ma´laga Ma´laga, Spain
Pilar Lo´pez-Larrubia Instituto de Investigaciones Biome´dicas “Alberto Sols” CSIC/UAM Madrid, Spain
Networking Research Center on Bioengineering Biomaterials and Nanomedicine, CIBER-BBN Ma´laga, Spain
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7530-3 ISBN 978-1-4939-7531-0 (eBook) https://doi.org/10.1007/978-1-4939-7531-0 Library of Congress Control Number: 2017962639 © Springer Science+Business Media, LLC 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media, LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface Magnetic resonance imaging (MRI), the most versatile of all in vivo imaging modalities, was born in 1973, when the Nobel Prize awardees, Paul C. Lauterbur and Peter Mansfield, at the State University of New York and the University of Nottingham, published their
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