Current Topics in Microbiology and Immunology Volume 72

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72 Edited ry W. Arber, Basle . W. Henle, Philadelphia. P. H. Hofschneider, Martinsried

J. H. Humphrey, London' N. K. ferne, Basle . P. Koldovskfh Philadelphia H.Koprowski, Philadelphia· O.Maaloe, Copenhagen· R.Rott, GiejJen· H. G.Schweiger, Wilhelmshaven· M. Sela, Rehovot· L. Syrucek, Prague· P. K. Vogt, Los Angeles

With 27 Figures

Springer-Verlag Berlin. Heidelberg. New York 1975

ISBN-13: 978-3-642-66291-1 DOl: 10.1007/978-3-642-66289-8

e-ISBN-13: 978-3-642-66289-8

This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under § 54 of the German Copyright Law where copies are made for other private use, a fee is payable to the publisher, the amount of the fee to be determined by agreement with the publisher. © by Springer-Verlag, Berlin· Heidelberg 1975. Library of Congress Catalog Card Number 15-12910. Softcover reprint of the hardcover 1st edition 1975

The nse of registered names, trademarks, etc. in this publication, does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Universitatsdruckerei H. Stiirtz AG, Wiirzburg

Table of Contents ANDERSEN, H. A., RASMUSSEN, L., and ZEUTHEN, E., Cell Division and DNA Replication in Synchronous Tetrahymena Cultures. . . . . .

1

BALDWIN, R W., and ROBINS, R A., Humoral Factors Abrogating CellMediated Immunity in the Tumor-Bearing Host

21

ASHERSON, G. L., and ZEMBALA, M., Inhibitory T Cells

55

HAASE, A. T., The Slow Infection Caused by Visna Virus

101

PILCH, Y. H., FRITZE, D., WALDMAN, S. R, and KERN, D. H., Transfer of Antitumor Immunity by "Immune" RNA

157

Subject Index. . . . . . . . . . • . . . • .

191

Cell Division and DNA Replication in Synchronous Tetrahymena Cultures H. A. ANDERSEN, LEIF RASMUSSEN, and ERIK ZEUTHEN 1 With 7 Figures

Table of Contents I. Introduction. . . . . .

1

II. Induction of Synchronous Cell Division by Means of Temperature Shocks A. Cultures Exposed to a Series of Heat Shocks Prior to Cell Divisions . B. Cultures Exposed to One Heat Shock per Cell Generation. . . . . . III. Other Methods for Induction of Synchronous Cell Divisions in Tetrahymena IV. DNA Replication in Tetrahymena. . . . . . . . . . . . . . . . . . . . A. DNA Synthesis in Cultures Exposed to Seven Heat Shocks Prior to Divisions B. DNA Synthesis in Cultures Exposed to One Heat Shock per Cell Generation C. DNA Synthesis in Selection-Synchronized Cells . . . . . . . . . . . . . D. DNA Synthesis in Tetrahymena Cells Synchronized by Starvation/Refeeding E. DNA Synthesis in Cells Synchronized by Other Means . . . . . . . . . . F. DNA Synthesis and Cell Division . . . . . . . . . . . . . . . . . . . G. The Effect of 5-Bromodeoxyuridine on DNA and RNA Synthesis in Tetrahymena. . . . . V. Concluding Remarks References.

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