NF-kB in Health and Disease

This volume is focused on a transcription factor that started its life as a B cell-specific nuclear protein, but has matured to become one of the most extensively studied transcriptional regulators, found to control many pathophysiological processes: NF-k

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Series Editors Klaus Aktories Medizinische Fakultät, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Albert-Ludwigs-Universität Freiburg, Abt. I, Albertstr. 25, 79104, Freiburg, Germany Richard W. Compans Department of Microbiology and Immunology, Emory University School of Medicine, 3001 Rollins Research Center, Atlanta, 30322, GA, USA Max D. Cooper Department of Pathology and Laboratory Medicine, Georgia Research Alliance, Emory University, 1462 Clifton Road, Atlanta, 30322, GA, USA Yuri Y. Gleba ICON Genetics AG, Biozentrum Halle, Weinbergweg 22, Halle, 6120, Germany Tasuku Honjo Department of Medical Chemistry, Faculty of Medicine, Kyoto University, Sakyo-ku, Yoshida, Kyoto, 606-8501, Japan Hilary Koprowski Department of Cancer Biology, Biotechnology Foundation Laboratories, Thomas Jefferson University, 1020 Locust Street, Suite M85 JAH, Philadelphia, PA, 19107-6799, USA Bernard Malissen Centre d’Immunologie de Marseille-Luminy, Parc Scientifique de Luminy, Case 906, 13288, Marseille Cedex 9, 13288, France Fritz Melchers Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany Michael B.A. Oldstone Viral Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines, La Jolla, CA, 92037, USA Sjur Olsnes Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello 0310, Oslo, Norway Peter K. Vogt Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC-239, La Jolla, CA, 92037, USA

Current Topics in Microbiology and Immunology Previously published volumes Further volumes can be found at springer.com Vol. 322: Romeo, Tony (Ed.): Bacterial Biofilms. 2008. ISBN 978-3-540-75417-6 Vol. 323: Tracy, Steven; Oberste, M. Steven; Drescher, Kristen M. (Eds.): Group B Coxsackieviruses. 2008. ISBN 978-3-540-75545-6 Vol. 324: Nomura, Tatsuji; Watanabe, Takeshi; Habu, Sonoko (Eds.) Humanized Mice. 2008 ISBN 978-3-540-75646-0

Vol. 336: Kielian, Tammy (Ed.): Toll-like Receptors: Roles in Infection and Neuropathology. 2009. ISBN 978-3-642-00548-0 Vol. 337: Sasakawa, Chihiro (Ed.): Molecular Mechanisms of Bacterial Infection via the Gut. 2009. ISBN 978-3-642-01845-9 Vol. 338: Rothman, Alan L. (Ed.): Dengue Virus. 2009. ISBN 978-3-642-02214-2

Vol. 325: Shenk, Thomas E.; Stinski, Mark F. (Eds.): Human Cytomegalovirus. 2008. ISBN 978-3-540-77348-1

Vol. 339: Spearman, Paul; Freed, Eric O. (Eds.): HIV Interactions with Host Cell Proteins. 2009. ISBN 978-3-642-02174-9

Vol. 326: Reddy, Anireddy S.N; Golovkin, Maxim (Eds.): Nuclear pre-mRNA processing in plants. 2008 ISBN 978-3-540-76775-6

Vol. 340: Saito, Takashi; Batista, Facundo D. (Eds.): Immunological Synapse. 2010. ISBN 978-3-642-03857-0

Vol. 327: Manchester, Marianne; Steinmetz Nicole F. (Eds.): Viruses and Nanotechnology. 2008. ISBN 978-3-540-69376-5 Vol. 328: van Etten, (Ed.): Lesser Known Large dsDNA Viruses. 2008. ISBN 978-3-540-68617-0 Vol. 329: Griffin