The Surfaceome Methods and Protocols
This volume provides readers with the latest techniques and tools to assess modifications and functions of the surfaceome. The chapters in this book are divided into 4 sections: discovery-based approaches to surfaceome content; targeted approaches for sur
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Kenneth R. Boheler Rebekah L. Gundry Editors
The Surfaceome Methods and Protocols
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
The Surfaceome Methods and Protocols
Edited by
Kenneth R. Boheler School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China; Stem Cell & Regenerative Medicine Consortium, School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China
Rebekah L. Gundry Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, USA
Editors Kenneth R. Boheler School of Biomedical Sciences LKS Faculty of Medicine The University of Hong Kong Hong Kong, SAR, China
Rebekah L. Gundry Department of Biochemistry Medical College of Wisconsin Milwaukee, WI, USA
Stem Cell & Regenerative Medicine Consortium, School of Biomedical Sciences LKS Faculty of Medicine The University of Hong Kong Hong Kong, SAR, China
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7551-8 ISBN 978-1-4939-7553-2 (eBook) https://doi.org/10.1007/978-1-4939-7553-2 Library of Congress Control Number: 2017960803 © Springer Science+Business Media, LLC 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media, LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface The plasma membrane is the gateway through which cells sense and respond to their microenvironment. Critical to this process are cell surface proteins that span (transmembrane) or are anchored/embedded in the plasma membrane. Cell sur
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