Antimicrobial, radical scavenging, and dye degradation potential of nontoxic biogenic silver nanoparticles using Cassia
- PDF / 1,687,464 Bytes
- 13 Pages / 595.276 x 790.866 pts Page_size
- 91 Downloads / 187 Views
ORIGINAL PAPER
Antimicrobial, radical scavenging, and dye degradation potential of nontoxic biogenic silver nanoparticles using Cassia fistula pods Indu Singh1,3 · Seema Gupta3 · Hemant K. Gautam1 · Gagan Dhawan3 · Pradeep Kumar2 Received: 9 July 2020 / Accepted: 12 September 2020 © Institute of Chemistry, Slovak Academy of Sciences 2020
Abstract Synthesis of metallic nanoparticles via green approach holds great potential in diverse fields of biotechnology and medicine with special mention to silver nanoparticles (AgNPs) which undoubtedly display antimicrobial, radical scavenging, and dye degradation properties. Currently, there is a need to explore more cost-effective and efficient methods to synthesize AgNPs. In this study, we have synthesized biogenic AgNPs using an aqueous extract of a flowering plant of the legume family, Fabaceae, subfamily Caesalpiniaceae, Cassia fistula, which is also well known for its medicinal values. Spectroscopically and physicochemically characterized AgNPs were evaluated for their cytocompatibility, antimicrobial effects, antioxidant and catalytic activity to establish their potential for various biomedical applications. DLS studies revealed their size ~ 237 nm with the surface charge of ~ − 30 mV. The results of the zone of inhibition and MIC assays showed the superiority of the activity of these particles over the pod extract. Catalytic reduction of toxic p-nitrophenol to benign p-aminophenol as well as degradation of hazardous industrial dyes (methyl orange and methylene blue) advocated their potential as environmental toxicant eradicators. Besides, these biogenic AgNPs displayed profound antibiofilm effects in static microtiter plates. Altogether, the results of various bioassays using these biogenic nanoparticles demonstrate their immense potential as antimicrobial, antioxidant, and antibiofilm agents. Keywords Cassia fistula (amaltas) · Silver nanoparticles · Antimicrobial · Antioxidant · Catalytic reduction · Antibiofilm effect
Introduction Presently, the use of conventional physical and chemical methods for the synthesis of metallic or metallic oxide nanoparticles (NPs) has reached the bare minimum as these methods are hazardous for living organisms and the surrounding environment (Das et al. 2017). The green synthesis with its tremendous potential is being counted as a better approach, especially, for some metallic nanoparticles, viz., gold, silver, selenium, iron. Green synthesis has reasonable merits over other physical and chemical methods, such as eco-friendly, * Pradeep Kumar [email protected] 1
CSIR-Institute of Genomics and Integrative Biology, Mathura Road, Delhi 110020, India
2
CSIR-Institute of Genomics and Integrative Biology, Mall Road, Delhi 110007, India
3
Acharya Narendra Dev College, University of Delhi, Govindpuri, Kalkaji, New Delhi 110019, India
inexpensive, less reaction time consuming with well-defined surface morphology, effective and efficient to uplift the scope of biomedical nanotechnology. In the current scenario, green chemistr
Data Loading...
