Dexamethasone
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Generalised maculopapular exanthema: case report An 80-year-old man developed generalised maculopapular exanthema following treatment with dexamethasone. The man, who had undergone dental implant surgery started receiving treatment with oral dexamethasone [dosage not stated], metronidazole and clindamycin. He developed generalised maculopapular exanthema 48 hours after starting dexamethasone. He was diagnosed with dexamethasone associated cutaneous adverse drug reaction (CADR). The man’s treatment with dexamethasone was discontinued and the generalised maculopapular exanthema resolved over 7 days. Intradermal testing with dexamethasone was positive and negative for clindamycin and metronidazole. Additional testing with other steroids revealed positive results for dexamethasone [dexamethasone disodium phosphate], tixocortol [tixocortol pivalate], hydrocortisone and methylprednisolone. Author comment: "Here, we report a novel case of a [cutaneous adverse drug reactions] induced by oral dexamethasone". Watts TJ, et al. Cutaneous adverse drug reaction induced by oral dexamethasone with possible cross-reactivity to Group 1 corticosteroids confirmed by patch testing and intradermal testing. Contact Dermatitis 81: 384-386, No. 5, Nov 2019. Available from: URL: http://doi.org/10.1111/cod.13334 - United 803437032 Kingdom
0114-9954/19/1781-0001/$14.95 Adis © 2019 Springer Nature Switzerland AG. All rights reserved
Reactions 30 Nov 2019 No. 1781
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