Dexamethasone
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Dexamethasone Ocular hypertension following phakic intraocular lens implantation: case report A 24-year-old woman developed elevated intraocular pressure (IOP) after receiving dexamethasone postoperatively following phakic intraocular lens implantation in the left eye. The woman was treated with local 0.1% dexamethasone [dosage not stated] and ofloxacin four times daily after surgery. One week later, local treatment was reduced to dexamethasone twice daily. One month after surgery she presented with a sudden loss of visual acuity in the left eye. Her uncorrected visual acuity had decreased to 20/32 (from 20/25 1 week after surgery) with an astigmatic change of about 3 D of cyl from previous assessment. Her IOP was 45mm Hg (compared with 18mm Hg 1 week after surgery). Dexamethasone was discontinued, and the woman was treated with apraclonidine and oral acetazolamide. Three days later, she had an uncorrected visual acuity of 20/20 and IOP of 10mm Hg. Acetazolamide was discontinued but she continued to received apraclonidine for another month. Follow-up examinations up to 12 months showed no further increase in IOP. Eschstruth P, et al. Sudden refractive change 1 month after phakic intraocular lens implantation. Acta Ophthalmologica 88: e19, No. 2, Mar 2010. Available from: 803013911 URL: http://dx.doi.org/10.1111/j.1755-3768.2008.01350.x - Germany
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Reactions 15 May 2010 No. 1301
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