Inflammation Methods and Protocols
This volume presents a broad selection of cutting-edge methods and tools that will enable the reader to investigate the multi-faceted manifestations of inflammation. Inflammation: Methods and Protocols is divided into four sections: the first th
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Björn E. Clausen Jon D. Laman Editors
Inflammation Methods and Protocols
Methods
in
Molecular Biology
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Inflammation Methods and Protocols
Edited by
Björn E. Clausen Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
Jon D. Laman Section Medical Physiology, Department of Neuroscience, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Editors Björn E. Clausen Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-University Mainz Mainz, Germany
Jon D. Laman Section Medical Physiology Department of Neuroscience University of Groningen University Medical Center Groningen Groningen, The Netherlands
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-6784-1 ISBN 978-1-4939-6786-5 (eBook) DOI 10.1007/978-1-4939-6786-5 Library of Congress Control Number: 2016961693 © Springer Science+Business Media LLC 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface Inflammation is part of a complex defense reaction of live tissues to injury. It is triggered by harmful stimuli, including pathogens, physical trauma, radiation, and chemical irritants. Inflammation is largely mediated by innate and adaptive immune cells in their efforts to eliminate the initial cause of tissue injury, clear out dead or infected cells, and facilitate tissue repair and wound healing. Hence, acute inflammation is beneficial to the host and must be tightly regulated. Too little inflammation may lead to progre
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