• PDF / 15,538,353 Bytes
• 363 Pages / 504.63 x 737.01 pts Page_size
• 55 Downloads / 209 Views

DOWNLOAD

REPORT

---

Natasha S. Barteneva Ivan A. Vorobjev Editors

Cellular Heterogeneity Methods and Protocols

Methods

in

Molecular Biology

Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK

For further volumes: http://www.springer.com/series/7651

Cellular Heterogeneity Methods and Protocols

Edited by

Natasha S. Barteneva PCMM-Harvard Medical School, Boston Children’s Hospital, Boston, MA, USA; Department of Biology, School of Sciences and Technology, Nazarbayev University, Astana, Kazakhstan

Ivan A. Vorobjev Department of Biology, School of Sciences and Technology, Nazarbayev University, Astana, Kazakhstan

Editors Natasha S. Barteneva PCMM-Harvard Medical School Boston Children’s Hospital Boston, MA, USA Department of Biology School of Sciences and Technology Nazarbayev University Astana, Kazakhstan

Ivan A. Vorobjev Department of Biology School of Sciences and Technology Nazarbayev University Astana, Kazakhstan

ISSN 1064-3745     ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7679-9    ISBN 978-1-4939-7680-5 (eBook) https://doi.org/10.1007/978-1-4939-7680-5 Library of Congress Control Number: 2018930254 © Springer Science+Business Media, LLC 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media, LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.

Dedication To the memory of Anatoly Shatkin (1928–1994), colleague and mentor, and to all my mentors: Thank you. Natasha S. Barteneva To the memory of my grandmothers and to my dad whose outstanding and dramatic fates I have always drawn upon as the source of inspiration to work. Ivan A. Vorobjev

v

Preface “The more specific idea of Evoluti